Platelet rich plasma (RICH PLASMA, PRP) therapy in orthopedics, dentistry and dermatology

 

 

WHAT IS PLATE-RICH PLASMA?

Platelet-rich plasma mesotherapy is an autologous procedure, i.e. one in which a preparation taken from the patient's tissues - in this case, blood - is used for the treatment purposes. PRP ( Platelet Rich Plasma ) is an excellent therapy, successfully used in orthopedics, cardiology, ophthalmology and dermatology.

 

WHAT EFFECTS SHOULD BE EXPECTED AFTER THE TREATMENT?

During the procedure, we use platelets that are responsible for regenerative processes. At the same time, they are equipped with growth factors that, released during the treatment, increase the number of fibroblasts that produce collagen fibers and stimulate the process of angiogenesis, i.e. the formation of new capillaries. As a consequence, the skin is nourished and the treatment effects are visible to the naked eye.

 

HOW OFTEN SHOULD I PERFORM THE TREATMENT?

It is a very individual matter and depends on the individual condition of the client's skin. In order to obtain the best results, the treatment should be performed in a series of 2-5 treatments with an interval of 3 weeks - this is a type of intensive therapy for the skin. The treatment also gives an excellent "banquet" effect, because after the first treatment the effects of skin lightening, rejuvenation and freshness are visible.

 

WHAT STANDARDS SHOULD BE FULFILLED BY A PRP PRP OFFICE?

  1. Ordering blood counts - higher treatment effectiveness and exclusion of contraindications.
  2. Ask the person performing the procedure about the system on which the procedure will be performed - your safety is guaranteed.
  3. The medical certificate - visible on the class II B blood collection tube - ensures that the correct medical device is used for the procedure.
  4. Remember to fill in the medical interview card, during which you will learn about the essence of the procedure - you will be correctly qualified for it.
  5. After the procedure, you will receive a document with a sticker guaranteeing the correctness of the PRP procedure - PRODUCT IDENTIFIER.
  6. Remember to follow the post-treatment procedures that you were informed about by the person authorized to perform the treatment - a guarantee of your safety.

 

WHAT SHOULD THE CORRECT PRP PROCEDURE LOOK LOOK LIKE?

  1. The analysis of the test results and the calculation of the number of platelets in the plasma by the person performing the procedure - the doctor, on the basis of the morphology results, according to a special calculator, calculates the concentration of platelets in the separated plasma.
  2. Detailed interview and filling in the informed consent form. During the interview, you will learn what the post-treatment indications are.
  3. Collection of the appropriate amount of blood into a certified test tube.
  4. Centrifugation to separate the PRP plasma. Centrifugation separates the plasma containing platelets with valuable growth factors from unnecessary elements such as red blood cells.
  5. The doctor collects the plasma into a sterile, disposable syringe with a needle.
  6. As little time as possible must elapse between centrifugation and the collection of plasma into the syringe until the start of the procedure.
  7. Performing the procedure in accordance with previous arrangements during the interview and qualification for the procedure. The procedure itself is performed according to general medical procedures.

 

 

APPLICATION OF Platelet-rich plasma in the treatment of traumatic and orthopedic diseases

 

Platelet-rich plasma therapy prp-behandlung works great in the treatment of injuries, e.g. knee sprains, chronic tendon injuries and others. The innovative treatment can also benefit people with chronic joint diseases. 

Platelet-rich plasmait is a basic component of the natural process of defense and regeneration of the body in case of any injuries. It has great potential for tissue repair during the healing process, thanks to the so-called growth factors that particularly affect the reconstruction of muscles and tendons. As a result, some orthopedic conditions can be healed without surgery. The platelet-rich plasma  injection method used in orthopedics is based on the use of the body's ability to regenerate. Stimulating our own cells to regenerate is possible thanks to the collection of our own blood. The procedure performed in the office is quick and safe for the patient,

Before the surgery

The most important thing is to see an orthopedic doctor. The specialist, on the basis of medical examinations and analysis of laboratory results, will decide whether the patient can undergo such therapy. Before the procedure of PRP administration, for about 2 weeks, non-steroidal anti-inflammatory drugs should be avoided, e.g. ibuprom, diclofenac or pyralgine. Instead, tramadol and paracetamol can be used. Do not take an anticoagulant drug 2-5 days before surgery. On the day of surgery, the Patient does not need to fast. Using a specially prepared set of 2 syringes, the doctor takes only about 10-20 ml of blood, which then, in a special separator, is precisely centrifuged, separating platelet-rich plasma from red blood cells. PRP is given by intraarticular or periarticular injection, if necessary under ultrasound guidance. The injection site is of course very thoroughly disinfected. Then a sterile dressing is put on. The patient is discharged home with specialist recommendations. PRP preparation does not impair psychomotor performance.

Recommendations after surgery

A few days after the procedure, local pain may occur - to alleviate the symptoms, you can use paracetamol or tramadol - the use of non-steroidal anti-inflammatory drugs (NSAIDs) should be absolutely avoided. Pain is related to the local reaction to the injection in the form of edema. Patients should lead a sparing lifestyle and avoid overloading the limb. In order to relieve pain, apply cold compresses several times a day for 10 to 20 minutes. Patients who perform non-strenuous, non-physical work can often return to it the next day. Orthopedic checks are necessary. The first one should take place 7 to 10 days from the date of the procedure and is of course included in the price of the procedure.

Efficacy of platelet-rich plasma in orthopedics

 

PRP-Treatment works by activating the platelets contained in platelet-rich plasma to produce specific growth factors. The effect is the stimulation of tissue regeneration processes, the creation of new blood vessels and the production of collagen. Thanks to this method, it is possible to restore damaged tissues and structures in cases such as:

  • tennis elbow
  • golfer's elbow
  • heel spurs
  • Jumper's knee (patellar ligament inflammation)
  • runner's knee
  • injuries / damage to tendons, muscles and ligaments,
  • degenerative changes in the Achilles tendon
  • injuries and overload changes
  • numerous diseases and injuries of joints - hip, knee, elbow, etc.
  • in fractures and non-union after fractures (the so-called pseudo-joints)
  • in order to accelerate the healing process of soft tissues - hard-to-heal wounds
  • goose foot tendinitis
  • bursitis of the greater trochanter of the femur
  • shoulder rotator cuff tendinopathy, subacromial isthmus syndrome
  • degenerative joint diseases

By giving PRP, we can also support the therapy:

  • articular cartilage defects: traumatic and degenerative
  • after reconstruction of the anterior cruciate ligament (ACL), suturing menisci, repair of articular cartilage
  • bone union disorders
  • hard to heal wounds, ulcers
  • postoperative: after repair procedures of tendons, eg Achilles.

Platelet rich plasma in dentistry

 

The concentration of growth factors was one of the first to deal with the dentist Dr. Robert Marx, who defined platelet-rich plasma as autogenous plasma in which the concentration of platelets exceeds the value in whole blood. According to its definition, the concentration should be at least 5 times higher, and two stages of centrifugation are necessary to obtain PRP.

Platelet-rich plasma is used in dentistry for tissue regeneration in periodontics and maxillofacial surgery.

Clinical trials have shown, inter alia, that PRP  reduces pain in functional disorders of temporomandibular joints  previously treated without success with the use of an occlusive splint. PRP injections can also be used as an adjunct therapy in the  treatment of blockage of the disc with reduction . Intra-articular administration of platelet-rich plasma showed better results than arthrocentesis in improving parameters such as the maximum range of mandibular abduction, reduction of acoustic phenomena and pain intensity.

The most spectacular application of PRP seems to be its use in the  surgical treatment of ankylosis of the temporomandibular joints . Traditionally, in advanced cases, a condylar ridge resection is performed, followed by its reconstruction with a sternoclavicular graft.

However, it seems that the therapeutic potential of PRP is the greatest in the  treatment of degenerative temporomandibular joints. and in these conditions the positive effect of platelet-rich plasma has been best proven. This is due to its composition and the resulting biological properties. Platelet-rich plasma contains substances called growth factors (GF), which are responsible for stimulating and initiating the processes of creating new cells and proteins. However, it is not just a simple concentrate of platelets and the platelet growth factors they contain. It also contains all the desired plasma components, including fibrin, fibronectin and vitronectin. These are important proteins from the point of view of tissue regeneration, responsible for e.g. for proper cell adhesion.